Biomass concentration is defined as the concentration of microbial cells in a culture at a given time. Biomass monitoring follows the development of the cell concentration over time and characterized growth of the cultured microorganism.
To record the development of biomass over time, various parameters (such as backscatter, absorbance, turbidity, optical density (OD), cell dry weight or cell number), but also synonyms for biomass (such as cell density and total cell density or TCD) are used. Whatever it is called, biomass is one of the most important critical process parameters (CPP) in microbial upstream bioprocessing.
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